Use a 20-mL (or larger) syringe and 20-gauge (or higher) needle. Reconstitute the 200 mg vial of ANDEXXA with 20 mL of Sterile Water for Injection (SWFI). Table 2: ANDEXXA Dose Based on Rivaroxaban or Apixaban Dose (Timing of Last Dose of FXa Inhibitor before ANDEXXA Initiation) FXa InhibitorÄetermine total number of vials required (see Table 1). The recommended dosing of ANDEXXA is based on the specific FXa inhibitor, dose of FXa inhibitor, and time since the patient's last dose of FXa inhibitor (see Table 2). * The safety and effectiveness of more than one dose have not been evaluated. The safety and efficacy of an additional dose have not been established. There are two dosing regimens (see Table 1).
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